JOURNAL 3187
Records of Natural Products
VOLUME & ISSUE
Year: 2024 Issue: 5 September-October
Year: 2024 Issue: 5 September-October
PAGES
p.490 - 498
p.490 - 498
STATISTICS
Viewed 273 times.
Viewed 273 times.
GRAPHICAL ABSTRACT
ABSTRACT
A new caffeoylquinic acid, 1, 5-di-O-caffeoyl-3-O-(1-O-methoxy-2-O-caffeoyl-4-maloyl)-quinic acid (1), and a new 5-hydroxymethylfurfural dimer, 5-(((2-methoxymethyl) furan-5-methanol) methyl) furan-2-carbaldehyde (2), were discovered from Arctium lappa roots. A comprehensive HRMS, UV, IR, 1D and 2D NMR techniques were used for structural identification. These two compounds had Nitric Oxide (NO) inhibitory activity in lipopolysaccharide (LPS)-stimulated RAW 264.7 inflammatory cell in a dose-dependent manner.
KEYWORDS
- Arctium lappa roots
- caffeoylquinic acid
- 5-hydroxymethylfurfural derivative
- anti-inflammatory activity