JOURNAL 3345


Records of Natural Products
VOLUME & ISSUE
Available Online: February 05,2025
PAGES
p.1 - 6
DOI ADDRESS
http://doi.org/10.25135/rnp.492.2410.3345
(DOI number will be activated after the manuscript has been available in an issue.)
STATISTICS
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AUTHORS
  • Min Ji
  • Yiqiao Wang
  • Yiming Wang
  • Xiaopo Zhang
  • Chengpeng Liu
  • Caiyun Zhang
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


A new dihydrophenanthrene (Spiranthol B), along with four known compounds, were isolated from Spiranthes sinensis. The new structure was determined by various spectroscopic analyses such as 1D, 2D NMR and HRMS techniques. Its stereochemistry was resolved by using the calculated electronic circular dichroism (ECD). Compounds 1-5 showed their capabilities to attenuate palmitic acid (PA)-induced reductions in MIN6 cells viability with the dosages of 3.125 and 6.25 μM.

KEYWORDS
  • Spiranthes sinensis
  • dihydrophenanthrenes
  • cell viability

SUPPORTING INFORMATION


Supporting Information
Download File 492-RNP-2410-3345-SI.pdf (2.55 MB)