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KHSO4-SiO2 catalyzed facile synthesis of bis(indolyl)methanes

Original Article

JOURNAL 1719

Organic Communications
VOLUME & ISSUE
Year: 2012 Issue: 3 July-September
PAGES
p.150 - 159
DOI ADDRESS
STATISTICS
Viewed 1973 times.
AUTHORS
    K. Reddi Mohan Naidu, Shaik Ibrahim Khalivulla, P. Chenna Rohini Kumar and Ola Lasekan
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GRAPHICAL ABSTRACT

ABSTRACT

This work presents a highly efficient and simple method for the synthesis of bis(indolyl)methanes, catalyzed by KHSO4-SiO2 with excellent yields. Various substituted aldehydes with indole under this reaction condition is elucidated. This method is an environmentally benign, efficient reaction, requires shorter reaction time and simple experimental and workup procedures.

 KEYWORDS
  • KHSO4-SiO2
  • aldehydes
  • indole
  • bisindolylmethanes
  • solvent-free reaction.