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Regioselective synthesis of new variety of 1,4-benzothiazines

Original Article

JOURNAL 682

Organic Communications
VOLUME & ISSUE
Year: 2014 Issue: 2 April-June
PAGES
p.77 - 84
STATISTICS
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AUTHORS
    Mohamed Saadouni, Tourya Ghailane, Said Boukhris, Amina Hassikou, Nouzha Habbadi, Rachida Ghailane, Mohamed Harcharras, Abdelaziz Souizi and Hassen Amri
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GRAPHICAL ABSTRACT

ABSTRACT

A facile and regioselective synthesis of 1, 4-benzothiazines was achieved with a variety of a -cyano a -alkoxy carbonyl epoxides and 2-aminothiophenol in the presence or no of HCl in the reaction medium. The structures of the newly synthesized compounds were confirmed by spectral studies.

 KEYWORDS
  • a -cyano a -alkoxy carbonyl
  • 2-aminothiophenol
  • regioselective
  • 1
  • 4-benzothiazines