JOURNAL 835


Organic Communications
VOLUME & ISSUE
Year: 2018 Issue: 1 January-March
PAGES
p.53 - 61
STATISTICS
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AUTHORS
    Flávio Valadares P. Borges, Roberto Mioso, Luíz André A. Silva, José Maria Barbosa-Filho, Gabrielly Diniz Duarte and Luís Cezar Rodrigues
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


Using classical reactions, the synthesis of seven natural esters was described, including for the first time the synthesis of four natural phenylpropanoid esters — compounds that have demonstrated promising bioactivity, proven by preliminary studies using samples obtained from natural sources. Applying the Wittig reaction, cis- and trans-bornyl ferulates were obtained, in an unusual manner, which established an alternative for the preparation of phenylpropanoid esters, especially in the synthesis of phenolic esters of tertiary alcohols such as the α- terpinyl trans-caffeate. The compounds obtained were identified and characterized by 1H-NMR and 13C-NMR spectroscopy.

KEYWORDS
  • Wittig reaction
  • esterification
  • phenylpropanoid esters

SUPPORTING INFORMATION


Supporting Information
Download File 6-OC-1802-065-SI.pdf (1.64 MB)