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Efficient one-pot three-component synthesis of 2H-indazole [2,1-b]phthalazine-1,6,11(13H)-triones at room temperature

Communication

JOURNAL 1768

Organic Communications
VOLUME & ISSUE
Year: 2020 Issue: 4 October-December
PAGES
p.194 - 201
DOI ADDRESS
http://doi.org/10.25135/acg.oc.85.20.08.1768
STATISTICS
Viewed 1904 times.
AUTHORS
  • Parshuram M. Pisal
  • Vinod T. Kamble
  • Ravi Varala
  • Pradip B. Gujarathi
PDF OF ARTICLE

GRAPHICAL ABSTRACT

ABSTRACT

Tetrabutylammonium bromide (TBAB) and cesium carbonate (Cs2O3) catalyzed, one-pot three-component synthesis of 2H-indazole[2,1b]phthalazine-1,6,11(13H)-triones was developed at room temperature in ethanol. Both electron donating and withdrawing groups are compatible under the optimized reaction parameters.

 KEYWORDS
  • TBAB;
  • Cs2CO3
  • indazole[2,1-b]phthalazine-1,6,11(13H)-triones
  • catalysis

SUPPORTING INFORMATION

Supporting Information
Download File A6-OC-2008-1768-SI.pdf (549.62 KB)