Zn(OAc)2•2H2O: An efficient catalyst for the one-pot synthesis of 2-substituted benzothiazoles
Year: 2022 Issue: 4 October-December
p.378 - 385
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By condensation from aldehyde and 2-aminothiophenol at 80 0C, environmentally friendly, easily accessible, and inexpensive Zn(OAc)2.2H2O (5 mol%) was used to synthesize electronically and structurally divergent benzothiazoles in moderate to good yields (67-96%). All the 2-substituted benzothiazole analogues were thoroughly characterized by IR, NMR and mass spectral analyses.KEYWORDS
- zinc acetate
- solvent-free condition