A review on some synthetic methods of 4(3H)-quinazolinone and benzotriazepine derivatives and their biological activities

Review Article

JOURNAL 3123

Organic Communications

VOLUME & ISSUE

Year: 2024 Issue: 2 April-June

PAGES

p.63 - 98

DOI ADDRESS

http://doi.org/10.25135/acg.oc.167..2402.3123

STATISTICS

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AUTHORS

Ahmed S. Abdelkhalek
Mansour E. Abokull
Samy M. Ibrahim
Mostafa K. Soltan
Mokhtar A. Abdul-malik
Shaban A. A. Abdel-Raheem

GRAPHICAL ABSTRACT

ABSTRACT

This concise review provides an overview of some synthetic methods utilized for the preparation of 4(3H)-quinazolinone and benzotriazepine derivatives, and explores their diverse biological activities. The review highlights the significance of these compounds in medicinal chemistry and discusses selected synthetic approaches employed in their synthesis. Additionally, it examines the range of biological activities exhibited by these derivatives and briefly discusses their potential applications. This succinct review serves as a valuable resource for researchers interested in the synthesis and biological evaluation of 4(3H)-quinazolinone and benzotriazepine derivatives.

KEYWORDS

Synthesis
heterocyclic compounds
4(3H)-quinazolinone
benzotriazepine
biological activities
medicinal chemistry