JOURNAL 241


Records of Natural Products
VOLUME & ISSUE
Year: 2009 Issue: 2 April-June
PAGES
p.96 - 103
STATISTICS
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AUTHORS
    Wanjala W. Cornelius, Teresa Akeng’a, George O Obiero and Kweyu P. Lutta
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GRAPHICAL ABSTRACT


ABSTRACT


The antifeedant activities of the Erythrina alkaloids from the seeds, seed pods and flowers of Erythrina latissima were investigated in laboratory dual- choice bioassays using third-instar Spodoptera littoralis (Boisduval) larvae. The new compound (+)-11β-methoxy-10-oxoerysotramidine (1) from the flowers, showed potent dose dependant activity at concentration >=500 pm while (+)-10,11-dioxoerysotramidine (2) also new from the flowers showed potent dose dependant activity at concentration >= 100 ppm. Three known compounds (+)-erysotrine, (+)-erysotramidine, (+)-erythraline, (+)-11β-hydroxyerysotramidine showed potent dose dependant antifeedant activity at concentrations >= 100 ppm while (+)-10,11-dioxoerysotrine and (+)-11 b-hydroxyerysotramidine also a known compounds showed potent dose dependant antifeedant activity at concentrations >= 100 ppm. Three known compounds (+)-11β-methoxyerysotramidine, (+)-8-oxoerythraline and (+)-15(16) b -D-glucoerysodine showed no appreciable change in antifeedant activity with concentration change.

KEYWORDS
  • P Erythrina alkaloids
  • Erythrina latissima
  • antifeedant activity
  • Spodoptera littoralis.