JOURNAL 242


Records of Natural Products
VOLUME & ISSUE
Year: 2009 Issue: 2 April-June
PAGES
p.104 - 109
STATISTICS
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AUTHORS
    Ibrahim Demirtas, Ayse Sahin, Bulent Ayhan, Saban Tekin and Isa Telci
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


Methanol extract from aerial parts of Sideritis libanotica Labill. subsp. linearis (Bentham) Borm. were investigated for its in vitro antiproliferative activities against Vero, HeLa and C6 cells. The tests were carried out as dose-dependent assay starting from 25 µg/mL to 250 µg/mL. The extract found to be active against African green monkey kidney (Vero), human uterus carcinoma (HeLa) and Rat Brain tumor cells (C6) cancer cell lines with IC 50 values. The methanol extract of S. libanotica showed the highest activity against the Vero, HeLa and C6 cell lines at 250 µg/mL as dose-dependent assay starting from 25 µg/mL.

KEYWORDS
  • Antiproliferation
  • Sideritis libanotica
  • Vero cells
  • plant extracts.