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Isolation, Characterization and Antioxidant, Tyrosinase Inhibitory Activities of Constituents from the Flowers of Cercis glabra ‘Spring-1’

Original Article

JOURNAL 1851

Records of Natural Products
VOLUME & ISSUE
Year: 2021 Issue: 4 July-August
PAGES
p.254 - 260
DOI ADDRESS
http://doi.org/10.25135/rnp.214.20.10.1851
STATISTICS
Viewed 1711 times.
AUTHORS
  • Penghua Shu
  • Yamin Li
  • Yuehui Luo
  • Shujing Cai
  • Yingying Fei
  • Wenhan Yi
  • Yuan Yang
  • Xialan Wei
  • Yuhuan Zhang
  • Tieyao Tu
  • Lin Zhang
PDF OF ARTICLE

GRAPHICAL ABSTRACT

ABSTRACT

A phytochemical study on the flowers of Cercis glabra ‘Spring-1’ led to the isolation and identification of twelve compounds, including one new compound named as 1-O-α-l-rhamnosyl-(E)-phytol (1) and eleven known compounds. Their structures were elucidated based on physical data analysis, including HR-ESI-MS, NMR, UV, IR, and acid hydrolysis. All compounds were screened for in vitro antioxidant activity using 2,2-diphenyl-1-picrylhydrazyl method. Compounds 4 and 5 exhibited obvious DPPH radical scavenging activities. All the isolates were tested for their inhibitory effects on mushroom tyrosinase, and compounds 6, 7, 10 and 11 showed moderate tyrosinase inhibitory activities. 

 KEYWORDS
  • Cercis glabra ‘Spring-1’
  • 1-O-α-l-rhamnosyl-(E)-phytol
  • antioxidant
  • tyrosinase.

SUPPORTING INFORMATION

Supporting Information
Download File A3-214-RNP-2010-1851-SI.pdf (1.8 MB)