JOURNAL 2017
Records of Natural Products
VOLUME & ISSUE
Year: 2022 Issue: 1 January-February
Year: 2022 Issue: 1 January-February
PAGES
p.84 - 91
p.84 - 91
STATISTICS
Viewed 1616 times.
Viewed 1616 times.
AUTHORS
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Bui Van Thanh
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Nguyen Thi Van Anh
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Chu Thi Thu Ha
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Do Hoang Giang
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Truong Thi Lien
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Ninh Khac Thanh Tung
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Nguyen Tien Dat
GRAPHICAL ABSTRACT
ABSTRACT
A novel 2,3-dioxygenated flavanone, dysosmaflavanone (2), along with five known phenolic compounds including podophyllotoxin (1), podoverin A (3), kaempferol (4), 8,2′-diprenyl quercetin 3-methyl ether (5), and ethyl β-D-glucoside (6) were isolated from the roots of the plant Dysosma difformis. Their structures were elucidated via spectroscopic analysis. Besides podophyllotoxin and kaempferol, the rest of the compounds were isolated from the genus Dysosma for the first time. Dysosmaflavanone, which possesses a rare 2,3-dioxygenated skeleton, could be regarded as an important chemotaxonomic marker. The antioxidant and antidiabetic activities of the isolated compounds were evaluated.
KEYWORDS- Dysosma difformis
- Berberidaceae
- 2,3-dioxygenated flavanone
- dysosmaflavanone
