JOURNAL 2075
Records of Natural Products
VOLUME & ISSUE
Year: 2022 Issue: 3 May-June
Year: 2022 Issue: 3 May-June
PAGES
p.206 - 211
p.206 - 211
STATISTICS
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Viewed 1747 times.
GRAPHICAL ABSTRACT
ABSTRACT
Two new 13-oxomilbemycins, 13-oxomilbemycin β3 (1) and 25-ethyl-13-oxomilbemycin β3 (2), were isolated from the broth of a NTG-induced mutation strain of Streptomyces avermitilis AVE-H39. The structures of 1 and 2 were determined based on MS and extensive NMR analysis. Compounds 1 and 2 possessed moderate nematocidal activity.
KEYWORDS- Streptomyces avermitilis AVE-H39
- NTG-induced mutation
- 13-oxomilbemycins
- nematocidal activity