Tigliane-Type Diterpenoids from the Seeds of Croton tiglium

Original Article

JOURNAL 2455

Records of Natural Products

VOLUME & ISSUE

Year: 2023 Issue: 2-March-April

PAGES

p.275 - 279

DOI ADDRESS

http://doi.org/10.25135/rnp.344.2205.2455

STATISTICS

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AUTHORS

Lijuan Zhang
Fei Li
Jianyong Zhu
Qian Niu

GRAPHICAL ABSTRACT

ABSTRACT

A new tigliane-type diterpenoid (1) and three known analogues (2-4) were isolated from the seeds of Croton tiglium. Extensive spectroscopic analyses, especially the 2D NMR experiments were used to determine their structures. The absolute configuration of 1 was defined by single-crystal X-ray diffraction data. The cytotoxicity 1-4 was evaluated against melanoma cell line A375, and the results showed that compounds 1, 3, and 4 exhibited certain cytotoxicities.

KEYWORDS

Croton tiglium
tigliane-type diterpenoid
cytotoxicity

SUPPORTING INFORMATION

Supporting Information

Download File A6-344-RNP-2205-2455-SI.pdf (950.75 KB)