JOURNAL 2628
Records of Natural Products
VOLUME & ISSUE
Year: 2023 Issue: 3 May-June
Year: 2023 Issue: 3 May-June
PAGES
p.501 - 508
p.501 - 508
STATISTICS
Viewed 1331 times.
Viewed 1331 times.
GRAPHICAL ABSTRACT
ABSTRACT
A phytochemical study on the Potamogeton pusillus L. led to the isolation and identification of a novel biflavonoid, pusillin A (1) with known seven compounds, including rosmarinic acid (2), luteolin-7-O-sulfate (3), eriodictyol-7-sulfate (4), chrysoeriol-7-sulfate (5), eriodictyol (5), luteolin (7) and chrysoeriol (8). Their structures were elucidated based on spectrometric analysis, including LC-MS/MS and NMR. All compounds were screened for in vitro antidiabetic activity using the spectrophotometric method. Sulfated flavones (1, 3, 4, and 5) exhibited prominent α-glucosidase inhibitory activity, and compounds 2, 6, 7, and 8 showed moderate inhibitory activities. All isolates were reported for the first time from the plant material.
- Potamogeton pusillus L
- biflavonoid
- α-glucosidase
- antidiabetic properties
- sulfated flavones
