JOURNAL 2525
Records of Natural Products
VOLUME & ISSUE
Year: 2023 Issue: 3 May-June
Year: 2023 Issue: 3 May-June
PAGES
p.509 - 515
p.509 - 515
STATISTICS
Viewed 2110 times.
Viewed 2110 times.
AUTHORS
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Qi Zhou
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Jiang Wan
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Chunxiao Jiang
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Yingpeng Tong
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Zhen-Da Xie
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Ting Wang
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Dao-An Xiao
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Zhi-Yong Xiao
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Jin-Feng Hu
GRAPHICAL ABSTRACT
ABSTRACT
A previously undescribed phenolic glycoside (manglycoside A, 1), as well as 16 identified compounds (2–17), were isolated from the leaves and twigs of the 'vulnerable' plant Magnolia decidua (Magnoliaceae). Comprehensive spectroscopicinvestigation and chemical transformations revealed the structure of the previously unknown compound 1. Among the isolates, honokiol (6) and liriodenine (14) were discovered to exhibit anti-inflammatory activities in LPS-induced RAW 264.7cells via reducing nitric oxide (NO) formation, with IC50 values of 4.3 and 17.3 μM, correspondingly.
KEYWORDS- Magnoliaceae
- Magnolia decidua
- phenolic glycoside
- aMnglycoside A
- anti-inflammatory
