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Mg(ClO 4) 2 catalyzed Eco-benign synthesis of 1,2,4-triazolinone derivatives as anti-tubercular agents

Original Article

JOURNAL 187

Organic Communications
VOLUME & ISSUE
Year: 2011 Issue: 4 October-December
PAGES
p.94 - 104
STATISTICS
Viewed 2291 times.
AUTHORS
    Dorababu Atukuri , Pramod Kattimani and Ravindra Kamble
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GRAPHICAL ABSTRACT

ABSTRACT

An eco-benign approach towards the synthesis of 1,2,4-triazolinones incorporated with isoindoline-1,3-dione (4a-j) and 9H-fluoren-9-imine (5a-j) was carried out using sydnones (1a-j) as synthon under magnesium perchlorate as catalyst . The newlysynthesized compounds were screened for anti-tubercular activities.

 KEYWORDS
  • Sydnone
  • isoindoline-1
  • 3-dione
  • fluroenone
  • Mg(ClO 4) 2
  • antitubercular activity.