JOURNAL 2492
Records of Natural Products
VOLUME & ISSUE
Year: 2023 Issue: 2-March-April
Year: 2023 Issue: 2-March-April
PAGES
p.363 - 366
p.363 - 366
STATISTICS
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Viewed 2580 times.
GRAPHICAL ABSTRACT
ABSTRACT
A new carotane sesquiterpene, trichocarotin N (1), was isolated from the culture of marine-derived fungus Trichoderma virens QD-11. Its structure was established by detailed analysis of 1D/2D NMR and HRESIMS data. Trichocarotin N (1) exhibited moderate cytotoxicity against HeLa and MCF-7 cancer cell lines, with IC50 values of 32.4 and 41.6 μM, respectively.
KEYWORDS- Trichoderma virens
- carotane sesquiterpeneT
- secondary metabolites
- cytotoxic activity
